Philipp Henneke

2012 W3-Professor Infection and Immunity, Head of Section for Pediatric Infectious Diseases and Rheumatology, CCI and Centre for Pediatrics, Freiburg
2008-2012 Tenure Track Infection and Immunity and group leader, CCI Freiburg
2005-2012 Attending Physician (“Oberarzt”) in Pediatric Infectious Diseases and Immunology, Centre of Pediatrics and Adolescent Medicine Freiburg
2003-2009 Assistant Prof. (“Juniorprofessor”) in Pediatric Infectious Diseases, University Medical Center, Freiburg
2001-2002 Lecturer, Harvard Medical School
2001-2002 Instructor/ Assistant Prof. in Medicine, Univ. of Massachusetts, Worcester, USA
1999-2001 Post doc at Division of Infectious Dis. and Immunology, Boston University, USA
1994-1999 Registrar in Pediatrics, Children’s Hospital, Freie Universität Berlin

PILOT Publications

A02 A07 ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA Greiner-Tollersrud OK, Krausz M, Boehler V, Polyzou A, Seidl M, Spahiu A, Abdullah Z, Andryka-Cegielski K, Dominick FI, Huebscher K, Goschin A, Smulski CR, Trompouki E, Link R, Ebersbach H, Srinivas H, Marchant M, Sogkas G, Staab D, Vågbø C, Guerini D, Baasch S, Latz E, Hartmann G, Henneke P, Geiger R, Peng XP, Grimbacher B, Bartok E, Alseth I, Warncke M, Proietti M. 2025 Cell Reports https://doi.org/10.1016/j.celrep.2024.114899
A02 A06 A07 B03 Reactive oxygen species regulate early development of the intestinal macrophage-microbiome interface Mansoori Moghadam Z, Zhao B, Raynaud C, Strohmeier V, Neuber J, Lösslein AK, Qureshi S, Gres V, Ziegelbauer T, Baasch S, Schell C, Warnatz K, Inohara N, Nunez G, Clavel T, Rosshart SP, Kolter J, Henneke P. 2025 Blood https://ashpublications.org/blood/article/doi/10.1182/blood.2024025240/535387/Reactive-oxygen-species-regulate-early-development
B03 B01 Metabolic rewiring tunes dermal macrophages in staphylococcal skin infection Forde AJ, Kolter J, Zwicky P, Baasch S, Lohrmann F, Eckert M, Gres V, Lagies S, Gorka O, Rambold AS, Buescher JM, Kammerer B, Lachmann N, Prinz M, Groß O, Pearce EJ, Becher B, Henneke P. 2023 Science Immunol https://www.science.org/stoken/author-tokens/ST-1371/full
B03 A02 B01 Neonatal immune challenge poses a sex-specific risk for epigenetic microglial reprogramming and behavioral impairment Schwabenland M, Mossad O, Sievert A, Peres AG, Ringel E, Baasch S, Kolter J, Cascone G, Dokalis N, Vlachos A, Ruzsics Z, Henneke P, Prinz M, Blank T. 2023 Nat Commun http://doi.org/10.1038/s41467-023-38373-0
A06 A03 Meconium Microbiome of Very Preterm Infants across Germany Jonas Klopp, Pamela Ferretti, Claudius U. Meyer, Katja Hilbert, Annette Haiß, Janina Marißen, Philipp Henneke, Hannes Hudalla, Sabine Pirr, Dorothee Viemann, Michael Zemlin, Sofia Kirke Forslund, Christoph Härtel, Peer Bork, Stephan Gehring, Thea Van Rossum, and the PRIMAL Consortium and Vincent B. Young 2022 mSphere https://journals.asm.org/doi/10.1128/msphere.00808-21
A01 A02 A04 A06 B02 B07 Perinatal development of innate immune topology. Philipp Henneke, Katrin Kierdorf, Lindsay J Hall, Markus Sperandio, Mathias Hornef 2021 eLife https://doi.org/10.7554/eLife.67793

PhilippHenneke,MD Professor

Projects

Director of the Institute for Infection Prevention and Control

Education

Scientific Qualifications

Professional Experience

PILOT Publications

ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA

Reactive oxygen species regulate early development of the intestinal macrophage-microbiome interface

Metabolic rewiring tunes dermal macrophages in staphylococcal skin infection

Neonatal immune challenge poses a sex-specific risk for epigenetic microglial reprogramming and behavioral impairment

Meconium Microbiome of Very Preterm Infants across Germany

Perinatal development of innate immune topology.

Philipp
Henneke,
MD Professor