Melanie Börries

Melanie
Börries,
MD, PhD Professor

melanie.boerries@uniklinik-freiburg.de

Project leader

Projects

University of Freiburg

Medical Center - University of Freiburg

Institute of Medical Bioinformatics and Systems Medicine

multi-omics, data analysis & RDM

Director of the Institute of Medical Informatics and Systems Medicine

PILOT Publications

A02 B02 Z01 Preimplantation factor (PIF) is an endogenous inhibitor of potassium channel KV1.3 regulating neutrophil function during pregnancy Roland Immler, Wiebke Nadolni, Johanna M Franz, Annika Bertsch, Sebastian Baasch, Vasilios A Morikis, Aleksandra Kurova, Marco Borso, Ignasi Forné, Ericka C M Itang, Johannes B Müller-Reif, Monika Pruenster, Lou M Wackerbarth, Matteo Napoli, Ina Rohwedder, Anna Yevtushenko, Michael Rauer, Martin Kolben, Markus Moser, Eytan Barnea, Melanie Boerries, Thomas Vogl, Scott I Simon, Claudia Klein, Philipp Henneke, Axel Imhof, Susanna Zierler, Markus Sperandio 2026 BioRxiv https://doi.org/10.64898/2026.03.20.713251
A06 B03 Z01 Macrophage renewal in the small intestine governs early-life control of streptococci Zohreh Mansoori Moghadam, Mirjam Freudenhammer, Maria Francesca Viola, Marleen Eckert, Candice Raynaud, Linus Kriegl, Michael Rauer, Reem Alsumati, Nicole Treichel, Ramona Rebekka Eckert, Sebastian Baasch, Melanie Boerries, Elvira Mass, Thomas Clavel, Daniel Erny, Julia Kolter, Philipp Henneke 2026 BioRxiv https://www.biorxiv.org/content/10.64898/2026.02.11.705249v1
A04 Z01 B01 Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface. Petry P, Oschwald A, Merkt S, Dinh TJ, Andrieux G, Crisand C, Botterer H, Nent E, Paterson N, Havermans M, Sankowski R, Schilling O, Boerries M, Amann L, Groß O, Schlitzer A, Prinz M, Lämmermann T, Kierdorf K. 2026 Developmental Cell https://doi.org/10.1016/j.devcel.2025.08.012
A04 B01 Z01 Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface Petry P, Oschwald A, Merkt S, Dinh TJ, Andrieux G, Crisand C, Botterer H, Nent E, Paterson N, Havermans M, Sankowski R, Schilling O, Boerries M, Amann L, Groß O, Schlitzer A, Prinz M, Lämmermann T, Kierdorf K 2025 Developmental Cell https://doi.org/10.1016/j.devcel.2025.08.012
A02 A06 Z01 Immunopathogenic and clinical implications of advanced tissue analysis in non-tuberculous mycobacterial infections in children Maximilian Seidl, Elham Bavafaye Haghighi, Anne Kathrin Lösslein, Markus Hufnagel, Florens Lohrmann, Christian Schneider, Daniela S Kohlfürst, Werner Zenz, Gregor Gorkiewicz, Cornelia Feiterna-Sperling, Renate Krüger, Peter Bronsert, Christina Neppl, Kim Zoe Sommer, Verena Stehl, Melanie Boerries, Martin Kuntz, Philipp Henneke 2025 Frontiers in Immunology https://doi.org/10.3389/fimmu.2025.1597074
A07 Z01 Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype Runge S, von Zedtwitz S, Maucher AM, Bruno P, Osbelt L, Zhao B, Gernand AM, Lesker TR, Gräwe K, Rogg M, Schell C, Boerries M, Strowig T, Andrieux G, Hild B, Rosshart SP 2025 Nature Communications https://doi.org/10.1038/s41467-025-60554-2
Z01 Phase II trial of hypomethylating agent combined with nivolumab for acute myeloid leukaemia relapse after allogeneic haematopoietic cell transplantation—Immune signature correlates with response Petya Apostolova, Stefanie Kreutmair, Cristina Toffalori, Marco Punta, Susanne Unger, Ann-Cathrin Burk, Claudia Wehr, Kristina Maas-Bauer, Wolfgang Melchinger, Eileen Haring, Rouven Hoefflin, Khalid Shoumariyeh, Valerie Hupfer, Eliza Maria Lauer, Sandra Duquesne, Theresa Lowinus, Nicolás Gonzalo Núñez, Chiara Alberti, Sara da Costa Pereira, Carla Helena Merten, Laura Power, Matthias Weiss, Caroline Böke, Dietmar Pfeifer, Reinhard Marks, Hartmut Bertz, Ralph Wäsch, Gabriele Ihorst, Bernhard Gentner, Justus Duyster, Melanie Boerries, Geoffroy Andrieux, Juergen Finke, Burkhard Becher, Luca Vago, Robert Zeiser 2023 British Journal of Haematology https://doi.org/10.1111/bjh.19007