Project Area B: Preprogrammed development

B05

Impact of intrauterine inflammation on neonatal dendritic cell development and function

Graphical abstract for Project B05
Graphical abstract for Project B05

In this project, we tackle the question of whether maternal inflammation shapes the dendritic cell (DC) compartment in the offspring via inflammatory cytokines. The project investigates the impact of prenatal inflammation on the origin, phenotype and function of the neonatal DC compartment. The time course of DC responsiveness to maternal inflammation will be characterized using fate mapping.

fate mapping

Team

Publications

B05